ISO 8661-1988 工业用己内酰胺挥发性碱含量的测定蒸馏后滴定法
时间:2024-05-22 18:40:46 来源: 标准资料网 作者：标准资料网 阅读：8918
【英文标准名称】:Caprolactamforindustrialuse;determinationofvolatilebasescontent;titrimetricmethodafterdistillation
【原文标准名称】:工业用己内酰胺挥发性碱含量的测定蒸馏后滴定法
【标准号】:ISO8661-1988
【标准状态】:现行
【国别】:国际
【发布日期】:1988-05
【实施或试行日期】:1988-05-15
【发布单位】:国际标准化组织(IX-ISO)
【起草单位】:ISO/TC47
【标准类型】:()
【标准水平】:()
【中文主题词】:容量分析;挥发物质;滴定法;含量测定;材料;化学分析和试验;化学分析;已内酰胺;己内酰胺
【英文主题词】:Caprolactam;Chemicalanalysisandtesting;Determinationofcontent;Materials;Titration;Volumetricanalysis
【摘要】:Thevolatilebasesaredistilledinalkalinemediumunderspecifiedconditionsandcollectedinaknownvolumeofastandardvolumetrichydrochloricacidsolutioninthepresenceofanindicator.Theexcessoftheacidistitratedwithastandardvolumetricsodiumhydroxidesolution.
【中国标准分类号】:G15
【国际标准分类号】:71_080_20
【页数】:6P.;A4
【正文语种】:英语
【英文标准名称】:Informationtechnology-Genericcablingforcustomerpremises;Amendment1
【原文标准名称】:信息技术.用户建筑群的通用布缆.修改件1
【标准号】:ISO/IEC11801AMD1-2008
【标准状态】:现行
【国别】:国际
【发布日期】:2008-04
【实施或试行日期】:
【发布单位】:国际标准化组织(IX-ISO)
【起草单位】:ISO/IECJTC1/SC25
【标准类型】:()
【标准水平】:()
【中文主题词】:建筑物服务设施;布线;通信电缆;计算机硬件;数据处理;数据传输;定义;电气装置;玻璃纤维电缆;信息交换;信息技术;接口(数据处理);场所;规范(验收)
【英文主题词】:Buildingservices;Cabling;Communicationcables;Computerhardware;Dataprocessing;Datatransmission;Definition;Definitions;Electricalinstallations;Glassfibrecables;Informationinterchange;Informationtechnology;Interfaces(dataprocessing);Locations;Specification(approval)
【摘要】:ThisstandardisInformationtechnology-Genericcablingforcustomerpremises;Amendment1.
【中国标准分类号】:M11;P92
【国际标准分类号】:35_110;35_200
【页数】:30P;A4
【正文语种】:英语
【英文标准名称】:StandardTestMethodforInVitroBiologicalActivityofRecombinantHumanBoneMorphogeneticProtein-2(rhBMP-2)UsingtheW-20MouseStromalCellLine
【原文标准名称】:使用W-20老鼠基质细胞系的重组体人骨形态形成蛋白-2(rhBMP-2)在实验室条件下的生物活性的标准试验方法
【标准号】:ASTMF2131-2002(2007)e1
【标准状态】:现行
【国别】:
【发布日期】:2002
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:F04.42
【标准类型】:(TestMethod)
【标准水平】:()
【中文主题词】:
【英文主题词】:invitrobioactivityassay;recombinanthumanbonemorphogeneticprotein;W-20cellline
【摘要】:AlthoughthetestmethodcanbeusedforassessmentofthebioactivityofcrudepreparationsofrhBMP-2,ithasonlybeenvalidatedforusewithhighlypure(>98%byweightproteinpurity)preparationsofrhBMP-2.1.1Thistestmethoddescribesthemethodusedandthecalculationofresultsforthedeterminationofthein-vitrobiologicalactivityofrhBMP-2usingthemousestromalcelllineW-20clone17(W-20-17).ThisclonewasderivedfrombonemarrowstromalcellsoftheW++mousestrain.1.2Thistestmethod(assay)hasbeenqualifiedandvalidatedbasedupontheInternationalCommitteeonHarmonizationassayvalidationguidelines(withtheexceptionofinterlaboratoryprecision)fortheassessmentofthebiologicalactivityofrhBMP-2.Therelevanceofthisinvitrotestmethodtoinvivoboneformationhasalsobeenstudied.ThemeasuredresponseintheW-20bioassay,alkalinephosphataseinduction,hasbeencorrelatedwiththeectopicbone-formingcapacityofrhBMP-2intheinvivoUseTest(UT).rhBMP-2thatwaspartiallyorfullyinactivatedbytargetedperaceticacidoxidationofthetwomethionineswasusedasatooltocomparetheactivities.OxidationofrhBMP-2withperaceticacidwasshowntobespecificallytargetedtothemethioninesbypeptidemappingandmassspectrometry.ThesemethioninesresideinahydrophobicreceptorbindingpocketonrhBMP-2.Oxidizedsampleswerecomparedalongsideanincubationcontrolandanativecontrol.The62,87,98,and100%oxidizedsampleshadW-20activitylevelsof62,20,7,and5%,respectively.Theincubationandnativecontrolsamplesmaintained100%activity.SampleswereevaluatedintheUTandshowedasimilareffectofinactivationonbone-formingactivity.Thesampleswith62%and20%activityintheW-20assaydemonstratedreducedlevelsofboneformation,similarinlevelwiththereductioninW-20specificactivity,relativetotheincubationcontrol.Littleornoectopicbonewasformedinthe7and5%activerhBMP-2implants.1.3Thus,modificationstotherhBMP-2moleculeinthereceptorbindingsitedecreasetheactivityinboththeW-20andUTassays.ThesedatasuggestthatasinglereceptorbindingdomainonrhBMP-2isresponsibleforbothin-vitroandin-vivoactivityandthattheW-20bioassayisarelevantpredictorofthebone-formingactivityofrhBMP-2.1.4ThevaluesstatedinSIunitsaretoberegardedasstandard.1.5Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.
【中国标准分类号】:C05
【国际标准分类号】:07_080
【页数】:6P.;A4
【正文语种】: